Rather, it details evidence that OxyContin does not last 12

July 21, 2013 Uncategorized

Purdue Pharma issues statement on OxyContin report

canada goose black friday sale Purdue Pharma issued a statement Friday defending its best selling painkiller, OxyContin, and criticizing a Los Angeles Times report that the medication wears off early in many patients, exposing them to increased risk of addiction. canada goose black friday sale

OxyContin main selling point is that it relieves pain for 12 hours. The Times investigation found that cheap Canada Goose when the effects don last, patients can suffer excruciating symptoms of narcotic withdrawal, including intense craving for the drug.

canada goose deals The article canada goose uk black friday said that Purdue had held fast buy canada goose jacket cheap to 12 hour dosing in part for financial reasons. OxyContin market dominance and premium price hinge on its 12 hour duration. canada goose deals

Canada Goose Jackets Purdue statement called the article on anecdotes and short on facts and said it was based on a theory. Manning, a Times spokeswoman, said: editors see nothing in Purdue statement that casts doubt on our reporting or our findings. She said the statement criticized The Times for omitting or disregarding information that in canadian goose jacket fact was included in the article. Canada Goose Jackets

Canada Goose online Here are Purdue complaints canada goose coats on sale about what it called The Times followed by the newspaper responses: Canada Goose online

canadian goose jacket OxyContin has a 12 hour dosing problem that puts patients at risk. Nearly a decade ago, a lack of clinical evidence when it formally rejected the premise canada goose clearance sale that patients receiving OxyContin at intervals more frequent than twice daily are at increased risk of cheap canada goose uk effects and serious adverse reactions. In doing so, the agency reinforced the twice daily labeling canada goose for OxyContin. The LAT omitted the findings of this report from its story. But it is consistent with The Times findings. canadian goose jacket

Canada Goose Parka The decision was the result of a regulatory dispute described in the article. The FDA had approved OxyContin as a 12 hour drug, although doctors can prescribe it for more frequent use to suit individual patients needs. Canada Goose Parka

canada goose store In a petition to the FDA, the Connecticut attorney general said that some doctors were prescribing OxyContin for Canada Goose online use every 8 hours, and that this was unsafe and was fueling black market sales of Canada Goose sale the drug. The state asked the FDA to add a warning to OxyContin product label prohibiting prescriptions for anything less than 12 hours. canada goose store

buy canada goose jacket cheap Purdue opposed the warning. Company lawyers acknowledged in their response to the petition that 8 hour dosing could treatment for some patients and should not be prohibited. Still, the lawyers said, the company planned to continue marketing the painkiller as a 12 hour drug. Among https://www.canadagoosepark.com Canada Goose Online the reasons the company cited was the advantage over painkillers that have to be taken more frequently. buy canada goose jacket cheap

buy canada goose jacket As The Times article noted, Purdue position that 8 hour dosing was best canada goose store for some patients stood in stark contrast to what its sales representatives had told doctors: that when patients complain about OxyContin wearing canada goose uk shop off early, uk canada goose outlet physicians should strengthen the dose and stick to the 12 hour schedule. buy canada goose jacket

Canada Goose sale The FDA rejected the Connecticut petition in 2008. It said physicians should retain the option to prescribe OxyContin at less than 12 hour intervals to suit patients needs. Canada Goose sale

canada goose The clinical data shows OxyContin is an 8 hour drug. Scientific evidence amassed over more than 20 years, including more than a dozen controlled clinical studies, supports the Canada Goose Coats On Sale FDA approval of 12 hour dosing for OxyContin. The OxyContin label has been updated more than 30 times and at no point did FDA request a change to the dosing frequency. In fact, the FDA approved label clearly states, are no well controlled clinical studies evaluating the safety and efficacy with dosing more frequently than every 12 hours. The Times report also describes clinical trials conducted by Purdue that found patients given OxyContin requested more pain medication in between 12 hour doses. In the first clinical trial, more than a third of patients who took canada goose black friday sale OxyContin complained about pain within eight hours, and about half had asked for more medication by the 12 hour mark. canada goose

cheap Canada Goose Purdue should tell physicians to prescribe OxyContin for eight hour use. The FDA prohibits pharmaceutical companies from promoting their products for uses, including dosing, not approved canada goose clearance by the agency. Given FDA has not approved OxyContin for eight hour use, we do not recommend that dosing to prescribers. In fact, a State Attorney General recently cited a peer company for falsely claiming that OxyContin was an eight hour drug. The LAT omitted this piece of information from its story. Rather, it details evidence that OxyContin does not last 12 hours in many patients, and it describes the potential consequences: withdrawal symptoms and an increased risk of addiction. The article makes clear that Purdue sought and received FDA approval of the canada goose factory sale painkiller as a 12 hour drug. It also notes that Purdue did not test OxyContin on other dosing schedules, although it could have. cheap Canada Goose

Canada Goose Outlet It rare for patients to take extended release drugs at different intervals. In a 2008 Times response Canada Goose Outlet

canada goose coats The article does not state that it is rare Canada Goose Parka for patients to take extended release drugs at different intervals. In fact, it makes the opposite point: Many physicians prescribe OxyContin for intervals shorter than 12 canada goose uk outlet hours when patients complain that the effects wear off sooner. The article explained that narcotic painkillers work differently in different people. It included an FDA spokeswoman statement that 12 hour dosing of OxyContin a reasonable starting point and that should carefully individualize their approach to patients based on how quickly they metabolize the drug. The LAT claims have not only been publicly voiced, uk canada goose they been directly buy canada goose jacket cheap canada goose Times response canada goose coats

canada goose clearance sale Much of the information in the article had not previously been published. The article drew on thousands of pages of internal Purdue records, many of which had been sealed by courts at Purdue request. The article acknowledges instances in which scientists or litigants raised questions about whether OxyContin lasts 12 hours. canada goose clearance sale

Regarding Purdue efforts to deter abuse of OxyContin by reformulating the pill and funding anti theft programs, they are described in the article.

canada goose clearance Purdue said The Times disregarded information that the company provided during than a dozen hours of briefings and discussions. The company canada goose coats arranged two phone briefings on 12 hour dosing with a Purdue executive, on condition the executive not be quoted and the information not be attributed to Purdue. The Times fully considered that information and included in its article the parts that were relevant and could be verified independently. Purdue provided a one page, on the record statement, portions of which are quoted in the story canada goose clearance.


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